

副教授
职称:副教授
学历:博士
邮箱:chenqi@ahmu.edu.cn
地址:合肥市瑶海区唐河路,安徽医科大学东校区,弘毅东楼
(一) 论文:
1. Yang Z, Liu C, Wang Y, Chen Y, Li Q, Zhang Y, Chen Q, Ju J*, Ma J*. MGCEP 1.0: A Genetic-Engineered Marine-Derived Chassis Cell for a Scaled Heterologous Expression Platform of Microbial Bioactive Metabolites. ACS Synth Biol. 2022 Nov 18;11(11):3772-3784.
2. Xie Y, Chen J, Wang B, Chen T, Chen J, Zhang Y, Liu X*, Chen Q*. Activation and enhancement of caerulomycin A biosynthesis in marine-derived Actinoalloteichus sp. AHMU CJ021 by combinatorial genome mining strategies. Microb Cell Fact. 2020 Aug 6;19(1):159.
3. Chen Q, Wu C, Zhang Y, Liu X, Chen J, Lei L, Xie Y*. Enhancement of marinacarboline A biosynthesis by optimizing the riboflavin supplement in marine derived Nocardiopsis flavescens CGMCC 4.5723. Biotechnol Lett. 2019 Sep;41(8-9):1033-1041.
4. Chen Q, Zhang S, Xie Y*. Characterization of a new microbial Pictet- Spenglerase NscbB affording the β-carboline skeletons from Nocardiopsis synnemataformans DSM 44143. J Biotechnol. 2018 Sep 10; 281:137-143.
5. Qin X, Xie Y, Huang H, Chen Q, Ma J, Li Q, Ju J*. Enzymatic Synthesis of GDP-α-l-fucofuranose by MtdL and Hyg20. Org Lett. 2018 Feb 16;20(4): 1015-1018.
6. Chen E, Chen Q, Chen S, Xu B, Ju J*, Wang H*. Mathermycin, a lantibiotic from the marine actinomycete Marinactinospora thermotolerans SCSIO 00652. Appl Environ Microbiol. 2017 Jul 17;83(15):e00926-17.
7. Zhu Q#, Chen Q#, Song Y, Huang H, Li J, Ma J, Li Q, Ju J*. Deciphering the sugar biosynthetic pathway and tailoring steps of nucleoside antibiotic A201A unveils a GDP-L-galactose mutase. Proc Natl Acad Sci USA. 2017 May 9;114(19):4948-4953.
8. Chen Q, Ji C, Song Y, Huang H, Ma J, Tian X, Ju J*. Discovery of McbB, an enzyme catalyzing the β-carboline skeleton construction in the marinacarboline biosynthetic pathway. Angew Chem Int Ed Engl. 2013 Sep 16;52(38):9980-9984.
9. Zhang Y, Huang H, Chen Q, Luo M, Sun A, Song Y, Ma J, Ju J*. Identification of the grincamycin gene cluster unveils divergent roles for GcnQ in different hosts, tailoring the L-rhodinose moiety. Org Lett. 2013 Jul 5;15(13):3254-3257.
10. Wang B, Song Y, Luo M, Chen Q, Ma J, Huang H, Ju J*. Biosynthesis of 9-methylstreptimidone involves a new decarboxylative step for polyketide terminal diene formation. Org Lett. 2013 Mar 15;15(6):1278-1281.
(二) 专利:
1. 陈奇,谢运昌,刘晓颖,滕衍斌,刘刚,张少飞,一种Pictet-Spengler酶及其编码基因与应用,中国发明专利,专利号:ZL 201810510161.3,2020年7月授权。
2. 鞠建华,陈奇,纪昌涛,一种海洋咔啉生物碱的生物合成基因簇及其应用,中国发明专利,专利号:CN 201310224447.2,2015年4月授权。
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